DVL1 Antikörper (Middle Region)

Produktnummer ABIN951918

Dieses Anti-DVL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DVL1 in WB, IF, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für DVL1 Antikörper (Middle Region) (ABIN951918)

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DVL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-DVL1 Antikörper

Bindungsspezifität: AA 441-470, Middle Region

Spezifität: This antibody recognizes Human Dishevelled-1 / DVL1 (Center).

Aufreinigung: Affinity Chromatography on Proteinn A

Immunogen: KLH conjugated synthetic peptide between 441-470 amino acids from the Central region of Human DVL1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DVL1

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Andere Bezeichnung: Dishevelled-1 / DVL1

Hintergrund: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.Synonyms: DSH homolog 1, DVL-1, Segment polarity protein dishevelled homolog DVL-1

Molekulargewicht: 75187 Da

Gen-ID: 1855

NCBI Accession: NP_004412

Pathways: WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development