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Cortactin Antikörper (N-Term)
CTTN
Reaktivität: Human
WB, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-Cortactin Antikörper
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Target
Alle Cortactin (CTTN) Antikörper anzeigen
Cortactin (CTTN)
Bindungsspezifität
Alle Epitope für Cortactin Antikörper
AA 16-46, N-Term
Reaktivität
Alle Reaktivitäten für Cortactin Antikörper
Human
Wirt
Alle Wirte für Cortactin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Cortactin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Cortactin Antikörper
Dieser Cortactin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Cortactin Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody recognizes Cortactin (SRC8) at N-term.
Kreuzreaktivität (Details)
Species reactivity (tested):Human
Aufreinigung
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 16-46aa) of human Cortactin (SRC8)
Isotyp
Ig Fraction
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Discover our top product CTTN Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu Cortactin
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Target
Cortactin (CTTN)
Andere Bezeichnung
Cortactin (CTTN Produkte )
Synonyme
EMS1 antikoerper, 1110020L01Rik antikoerper, Ems1 antikoerper, Cttnb antikoerper, CG3637 antikoerper, Dmel\CG3637 antikoerper, cortactin antikoerper, cttn antikoerper, CTTN1 antikoerper, P85.25 antikoerper, Cttn antikoerper, ems1 antikoerper, CTTN antikoerper, cortactin antikoerper, CG3637 gene product from transcript CG3637-RD antikoerper, cortactin S homeolog antikoerper, cortactin L homeolog antikoerper, src substrate cortactin antikoerper, Src substrate cortactin antikoerper, CTTN antikoerper, Cttn antikoerper, Cortactin antikoerper, cttn.S antikoerper, cttn.L antikoerper, cttn antikoerper, CpipJ_CPIJ006351 antikoerper, Bm1_57220 antikoerper, LOC100533277 antikoerper
Hintergrund
SRC8 (CTTN) is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.Synonyms: Amplaxin, CTTN, EMS1, Oncogene EMS1
Gen-ID
2017
NCBI Accession
NP_005222
Pathways
MAPK Signalweg
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