COPS8 Antikörper (N-Term)

Produktnummer ABIN951663

Dieses Anti-COPS8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von COPS8 in WB und EIA. Geeignet für Human.

Kurzübersicht für COPS8 Antikörper (N-Term) (ABIN951663)

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-COPS8 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Spezifität: This antibody reacts to COPS8.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human COPS8

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu COPS8

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Andere Bezeichnung: COPS8

Hintergrund: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Synonyms: COP9 signalosome complex subunit 8, CSN8, JAB1-containing signalosome subunit 8, SGN8, Signalosome subunit 8

Molekulargewicht: 23226 Da

Gen-ID: 10920

NCBI Accession: NP_006701

Pathways: Zellzyklus