Complement Factor I Antikörper (FITC)

Produktnummer ABIN951648

Produktdetails anti-Complement Factor I Antikörper (FITC)

Target: Complement Factor I (CFI)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement Factor I Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Spezifität: Anti-human factor I (C3b inactivator) monoclonal antibody clone OX-21 recognizes human complement protein factor I. Factor I has two polypeptide chains, 56 kDa and 36 kDa. This antibody detects only the 56 kDa chain. This clone has been reported not to cross react with rat.

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Human complement Factor I Donor: Immunized FI cross DBA/2 x BALB/c mouse spleen cells Fusion Partner: NS-1 mouse myeloma

Klon: OX-21

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu Complement Factor I

Target: Complement Factor I (CFI)

Andere Bezeichnung: Complement Factor I (CFI Produkte)

Hintergrund: Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement protein breakdown products: Factor H, CR1 and MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.Synonyms: AHUS3, C3B/C4B inactivator, C3BINA, C3b-INA, CFI, IF, KAF

Gen-ID: 3426

NCBI Accession: NP_000195

UniProt: P05156

Pathways: Komplementsystem