Complement C2 Antikörper (N-Term)

Produktnummer ABIN951633

Der Kaninchen Polyklonal anti-Complement C2 Antikörper (ABIN951633) detektiert spezifisch Complement C2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Hamster.

Kurzübersicht für Complement C2 Antikörper (N-Term) (ABIN951633)

Target: Complement C2

Reaktivität: Human, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Complement C2 Antikörper

Bindungsspezifität: AA 150-180, N-Term

Spezifität: This antibody reacts to Complement C2.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Hamster.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Complement C2

Target: Complement C2

Hintergrund: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.Synonyms: C2, C3/C5 convertase, Complement component 2

Gen-ID: 717

NCBI Accession: NP_000054