LILRB4 Antikörper (N-Term)

Produktnummer ABIN951418

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LILRB4 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LILRB4 Antikörper (N-Term) (ABIN951418)

Target: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-LILRB4 Antikörper

Bindungsspezifität: AA 43-73, N-Term

Spezifität: This antibody recognizes Human CD85K / LILRB4 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 43-73 amino acids from the N-terminal region of Human CD85K / LILRB4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LILRB4

Target: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Andere Bezeichnung: CD85k / LILRB4

Hintergrund: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: CD85 antigen-like family member K, HM18, ILT-3, ILT3, Immunoglobulin-like transcript 3, LILR-B4, LIR-5, LIR5, Leukocyte immunoglobulin-like receptor 5, Leukocyte immunoglobulin-like receptor subfamily B member 4, Monocyte inhibitory receptor HM18

Molekulargewicht: 49298 Da

Gen-ID: 11006

NCBI Accession: NP_001074907