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CD73 Antikörper

NT5E Reaktivität: Human FACS Wirt: Maus Monoclonal AD2 unconjugated
Produktnummer ABIN951383
  • Target Alle CD73 (NT5E) Antikörper anzeigen
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Reaktivität
    • 122
    • 74
    • 31
    • 18
    • 18
    • 16
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 91
    • 43
    • 22
    • 2
    Maus
    Klonalität
    • 81
    • 76
    • 1
    Monoklonal
    Konjugat
    • 65
    • 14
    • 12
    • 9
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD73 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 73
    • 50
    • 41
    • 16
    • 15
    • 14
    • 14
    • 12
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on T and B cell subsets, follicular dendritic cells and endothelial cells.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein A affinity chromatography
    Klon
    AD2
    Isotyp
    IgG1
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Andere Bezeichnung
    CD73 (NT5E Produkte)
    Hintergrund
    CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.Synonyms: 5'-nucleotidase, NT5, NT5E, NTE
    Gen-ID
    4907
    NCBI Accession
    NP_001191742
    UniProt
    P21589
    Pathways
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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