CD55 Antikörper (PE)

Produktnummer ABIN951352

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD55 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Primate.

Kurzübersicht für CD55 Antikörper (PE) (ABIN951352)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD55 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: MEM-118

Produktdetails anti-CD55 Antikörper (PE)

Spezifität: This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Non-Human Primates

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55 / DAF

Hintergrund: CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.Synonyms: Complement decay-accelerating factor

Gen-ID: 1604

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity