CD27 Antikörper (PE)
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- Target Alle CD27 Antikörper anzeigen
- CD27 (CD27 Molecule (CD27))
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD27 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Spezifität
- This Monoclonal Antibody is specific for the Mouse CD27 receptor.
- Immunogen
- MCD27 tag expressing clones AR0524 and AR0530 Donor: Armenian hamster spleen Fusion Partner: SP2/0 Murine Myeloma Partner
- Klon
- LG-3A10
- Isotyp
- IgG1
- Top Product
- Discover our top product CD27 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0,1 mg/mL
- Buffer
- PBS, 0.02 % Sodium Azide, EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE!
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- CD27 (CD27 Molecule (CD27))
- Andere Bezeichnung
- CD27 (CD27 Produkte)
- Hintergrund
- CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8-precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
- Gen-ID
- 21940
- NCBI Accession
- NP_001028298
- UniProt
- P41272
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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