CD247 Antikörper
Kurzübersicht für CD247 Antikörper (ABIN951241)
Target
Alle CD247 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Spezifität
- This antibody detects the zeta subunit of the T cell receptor (TCR).
-
Aufreinigung
- Protein G Affinity Chromatography.
-
Isotyp
- IgG
-
-
anti-CD247 Molecule (CD247) (pTyr72) antibody
CD247 Reaktivität: Human, Maus WB, ICC, ICFC Wirt: Maus Monoclonal EM-26 unconjugated
anti-CD247 Molecule (CD247) (AA 1-164) antibodyCD247 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-CD247 Molecule (CD247) (AA 1-164) antibodyCD247 Reaktivität: Human WB, ELISA, IP, IHC (p) Wirt: Maus Monoclonal 4A12-F6 unconjugated
anti-CD247 Molecule (CD247) (AA 88-153) antibodyCD247 Reaktivität: Human WB, ELISA, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-CD247 Molecule (CD247) (AA 50-164) antibodyCD247 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD247 Molecule (CD247) antibodyCD247 Reaktivität: Human ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 4B10 unconjugated
anti-CD247 Molecule (CD247) antibodyCD247 Reaktivität: Human WB, IHC, FACS Wirt: Kaninchen Monoclonal unconjugated
anti-CD247 Molecule (CD247) (AA 1-165) antibodyCD247 Reaktivität: Human WB, IP, IHC (p), EIA Wirt: Maus Monoclonal 4A12-F6 unconjugated
anti-CD247 Molecule (CD247) (AA 51-100) antibodyCD247 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD247 Molecule (CD247) (pTyr111), (pTyr123) antibodyCD247 Reaktivität: Human, Maus WB, FACS Wirt: Maus Monoclonal EM-55 unconjugated
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1.0 mg/mL
-
Buffer
- PBS containing 0.02 % Sodium Azide as preservative.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
-
- CD247 (CD247 Molecule (CD247))
-
Andere Bezeichnung
- CD247 / CD3Z
-
Hintergrund
- The TCR complex consists of a ligand specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma, delta, eta and zeta subunits. This complex regulates assembly and expression of the receptor and is thought to be responsible for transmembrane transduction of signals after binding to TCRαβ. Studies have suggested that the CD3z subunit (also know as CD247) plays an important role in two distinct cellular compartments. In the cytoplasm, it may function to regulate Ag receptor expression and in the plasma membrane it may be required for optimal signaling by the physiologic ligand Ag/MHC. The CD3z subunit is also associated with the CD16 IgG Fc receptor on NK cells.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ
-
Gen-ID
- 12503
-
Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Target
-
