CD235a/GYPA Antikörper

Produktnummer ABIN951236

Der Kaninchen Polyklonal Anti-CD235a/GYPA-Antikörper wurde für FACS, WB und EIA validiert. Er ist geeignet, CD235a/GYPA in Proben von Human zu detektieren.

Kurzübersicht für CD235a/GYPA Antikörper (ABIN951236)

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD235a/GYPA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CD235a/GYPA Antikörper

Spezifität: Anti-human Glycophorin A (GpA) Polyclonal Antibody targets the human Glycophorin A protein. This polyclonal antibody recognizes various epitopes on the GpA protein. The 23 residue hydrophobic transmembrane domain has been shown to mediate non-covalent dimerization of the protein under conditions of SDS page (and in other detergents). We also sell a FITC conjugated version of this antibody (AP31671FC-N).

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Human Glycophorin A transmembrane protein Donor: Rabbit serum

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD235a/GYPA

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Andere Bezeichnung: CD235a / GYPA

Hintergrund: This 131 amino acid, 36 KDa, transmembrane sialoglycoprotein spans the membrane of erythrocytes once. GpA presents its N terminus at the extracellular surface of the human red blood cell, has a single transmembrane domain and an internal cytoplasmic C terminus. GpA contributes to the expression of blood group antigen M and N specificities, which work to prevent red blood cell aggregation in circulation. Studies show that GpA is expressed early on the cell surface during erythropoiesis as pluripotent stem cells are recruited to differentiate into erythrocytes. This makes GpA a useful marker for studying the developmental biology of hematopoietic progenitor cells.Synonyms: GPA, Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha

Gen-ID: 2993

NCBI Accession: NP_002090

Pathways: Maintenance of Protein Location