nectin-3 Antikörper (C-Term)

Produktnummer ABIN951154

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch nectin-3 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für nectin-3 Antikörper (C-Term) (ABIN951154)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser nectin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-nectin-3 Antikörper

Bindungsspezifität: AA 514-544, C-Term

Spezifität: This antibody recognizes Human CD113 / Nectin 3 (C-term).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 514-544 amino acids from the C-terminal region of Human CD113 / Nectin 3. Genename: PVRL3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Andere Bezeichnung: CD113 / Nectin 3

Hintergrund: Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.Synonyms: CDw113, Nectin-3, PRR3, PVRL3, Poliovirus receptor-related protein 3

Molekulargewicht: 61002 Da

Gen-ID: 25945

NCBI Accession: NP_056295

Pathways: Cell-Cell Junction Organization