Endoglin Antikörper (Middle Region)
Kurzübersicht für Endoglin Antikörper (Middle Region) (ABIN951149)
Target
Alle Endoglin (ENG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 272-302, Middle Region
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Spezifität
- This antibody recognizes Human CD105 / Endoglin (Center).
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Aufreinigung
- Affinity Chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 272-302 amino acids from the Central region of Human CD105 / Endoglin. Genename: ENG
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Endoglin (ENG)
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Andere Bezeichnung
- CD105 / Endoglin
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Hintergrund
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: END, ENG, HHT1, ORW, ORW1
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Molekulargewicht
- 70578 Da
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Gen-ID
- 2022
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NCBI Accession
- NP_000109
Target
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