Cathepsin K Antikörper (Middle Region)

Produktnummer ABIN951065

Produktdetails anti-Cathepsin K Antikörper

Target: Cathepsin K (CTSK)

Bindungsspezifität: AA 96-126, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human Cathepsin K.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, MonkeySpecies reactivity (tested):Human

Aufreinigung: Saturated Ammonium Sulfate (SAS) Precipitation

Immunogen: KLH conjugated synthetic peptide between 96-126 amino acids from the Central region of Human Cathepsin K Genename: CTSK

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Cathepsin K

Target: Cathepsin K (CTSK)

Andere Bezeichnung: Cathepsin K (CTSK Produkte)

Synonyme: CTS02 antikoerper, CTSO antikoerper, CTSO1 antikoerper, CTSO2 antikoerper, PKND antikoerper, PYCD antikoerper, AI323530 antikoerper, MMS10-Q antikoerper, Ms10q antikoerper, catK antikoerper, CTSK antikoerper, wu:fa95f03 antikoerper, wu:fb08b05 antikoerper, zgc:110367 antikoerper, cts02 antikoerper, ctso antikoerper, ctso1 antikoerper, ctso2 antikoerper, pknd antikoerper, pycd antikoerper, OC-2 antikoerper, catk antikoerper, cathepsin K antikoerper, cathepsin K L homeolog antikoerper, Cathepsin K antikoerper, CTSK antikoerper, Ctsk antikoerper, ctsk antikoerper, ctsk.L antikoerper, catk antikoerper

Hintergrund: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq].Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Molekulargewicht: 36966 Da

Gen-ID: 1513

NCBI Accession: NP_000387

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades