Cathepsin K Antikörper (Middle Region)

Produktnummer ABIN951065

Der Kaninchen Polyklonal anti-Cathepsin K Antikörper wird verwendet zum Nachweis von Cathepsin K in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für Cathepsin K Antikörper (Middle Region) (ABIN951065)

Target: Cathepsin K (CTSK)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Cathepsin K Antikörper

Bindungsspezifität: AA 96-126, Middle Region

Spezifität: This antibody recognizes Human Cathepsin K.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, MonkeySpecies reactivity (tested):Human

Aufreinigung: Saturated Ammonium Sulfate (SAS) Precipitation

Immunogen: KLH conjugated synthetic peptide between 96-126 amino acids from the Central region of Human Cathepsin K Genename: CTSK

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Cathepsin K

Target: Cathepsin K (CTSK)

Andere Bezeichnung: Cathepsin K

Hintergrund: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq].Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Molekulargewicht: 36966 Da

Gen-ID: 1513

NCBI Accession: NP_000387

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades