RCAN1 Antikörper (N-Term)
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- Target Alle RCAN1 Antikörper anzeigen
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Bindungsspezifität
- AA 40-68, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RCAN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human RCAN1 (N-term).
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of Human RCAN1. Genename: RCAN1
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RCAN1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Andere Bezeichnung
- Calcipressin-1 (RCAN1 Produkte)
- Hintergrund
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this geneSynonyms: ADAPT78, CSP1, DSC1, DSCR1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, RCAN1, Regulator of calcineurin 1
- Molekulargewicht
- 28079 Da
- Gen-ID
- 1827
- NCBI Accession
- NP_004405
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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