RCAN1 Antikörper (N-Term)

Produktnummer ABIN951003

Dieses Anti-RCAN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RCAN1 in WB und EIA. Geeignet für Human.

Kurzübersicht für RCAN1 Antikörper (N-Term) (ABIN951003)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-RCAN1 Antikörper

Bindungsspezifität: AA 40-68, N-Term

Spezifität: This antibody recognizes Human RCAN1 (N-term).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of Human RCAN1. Genename: RCAN1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: Calcipressin-1

Hintergrund: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this geneSynonyms: ADAPT78, CSP1, DSC1, DSCR1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, RCAN1, Regulator of calcineurin 1

Molekulargewicht: 28079 Da

Gen-ID: 1827

NCBI Accession: NP_004405

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development