RCAN1 Antikörper (N-Term)

Produktnummer ABIN1539360

Produktdetails anti-RCAN1 Antikörper

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Bindungsspezifität: AA 41-68, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.

Klon: RB36242

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: RCAN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: RCAN1 (RCAN1 Produkte)

Synonyme: ADAPT78 antikoerper, CSP1 antikoerper, DSC1 antikoerper, DSCR1 antikoerper, MCIP1 antikoerper, RCN1 antikoerper, RCAN1 antikoerper, 2410048A02Rik antikoerper, AA408855 antikoerper, AI429645 antikoerper, AL024459 antikoerper, AV028423 antikoerper, Adapt78 antikoerper, CALP1L antikoerper, Dscr1 antikoerper, Mcip1 antikoerper, dscr1 antikoerper, rcan1 antikoerper, wu:fr92c05 antikoerper, adapt78 antikoerper, csp1 antikoerper, dsc1 antikoerper, mcip1 antikoerper, MGC53636 antikoerper, rcn1 antikoerper, MGC69428 antikoerper, regulator of calcineurin 1 antikoerper, regulator of calcineurin 1b antikoerper, regulator of calcineurin 1 L homeolog antikoerper, Down syndrome critical region gene 1 antikoerper, RCAN1 antikoerper, Rcan1 antikoerper, rcan1b antikoerper, rcan1.L antikoerper, dscr1 antikoerper, rcan1 antikoerper

Hintergrund: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Molekulargewicht: 28079

Gen-ID: 1827

NCBI Accession: NP_004405, NP_981962, NP_981963

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development