BHLHA15 Antikörper (C-Term)

Produktnummer ABIN950660

Der Kaninchen Polyklonal anti-BHLHA15 Antikörper wird verwendet zum Nachweis von BHLHA15 in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für BHLHA15 Antikörper (C-Term) (ABIN950660)

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BHLHA15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-BHLHA15 Antikörper

Bindungsspezifität: AA 167-197, C-Term

Spezifität: This antibody reacts to BHLHB8.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 167-197 amino acids from the C-terminal region of human BHLHA15

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BHLHA15

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Andere Bezeichnung: BHLHB8 / BHLHA15

Hintergrund: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).Synonyms: Class A basic helix-loop-helix protein 15, Class B basic helix-loop-helix protein 8, MIST1, Muscle, intestine and stomach expression 1

Gen-ID: 168620

NCBI Accession: NP_803238