BHLHA15 Antikörper (AA 60-110)

Produktnummer ABIN6991922

Produktdetails anti-BHLHA15 Antikörper

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Bindungsspezifität: AA 60-110

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BHLHA15 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: BHLHA15 antibody is human, mouse and rat reactive.

Aufreinigung: BHLHA15 antibody is affinity chromatography purified via peptide column.

Immunogen: BHLHA15 antibody was raised against a 18 amino acid peptide near the center of human BHLHA15. The immunogen is located within amino acids 60 - 110 of BHLHA15.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: BHLHA15 antibody can be used for detection of BHLHA15 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: BHLHA15 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: BHLHA15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu BHLHA15

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Andere Bezeichnung: BHLHA15 (BHLHA15 Produkte)

Synonyme: BHLHB8 antikoerper, MIST1 antikoerper, 1810009C13Rik antikoerper, Bhlhb8 antikoerper, MIST-1 antikoerper, Mist1 antikoerper, bHlH antikoerper, basic helix-loop-helix family member a15 antikoerper, basic helix-loop-helix family, member a15 antikoerper, BHLHA15 antikoerper, Bhlha15 antikoerper

Hintergrund: BHLHA15 (basic helix-loop-helix protein 15), also known as MIST1 (muscle intestine and stomach expression 1) belongs to the bHLH family of transcription factors and plays a role in regulating the transcriptional activity of MYOD1 in muscle cell development as well as serving as a key regulator of acinar cell function (1,2). BHLHA15 contains a basic helix-loop-helix (bHLH) domain and is capable of binding to E-box motifs as a homodimer or a heterodimer with E-proteins. It may also negatively regulate bHLH-mediated transcription through a N-terminal repressor domain (3). It is expressed in mammary epithelial cells and is essential for the regulation of mammary gland development (4).

Molekulargewicht: Predicted: 21 kDa

Observed: 24 kDa

Gen-ID: 168620

NCBI Accession: NP_803238

UniProt: Q7RTS1