BHLHA15 Antikörper (AA 60-110)
Kurzübersicht für BHLHA15 Antikörper (AA 60-110) (ABIN6991922)
Target
Alle BHLHA15 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 60-110
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Spezifität
- BHLHA15 antibody is human, mouse and rat reactive.
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Aufreinigung
- BHLHA15 antibody is affinity chromatography purified via peptide column.
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Immunogen
- BHLHA15 antibody was raised against a 18 amino acid peptide near the center of human BHLHA15. The immunogen is located within amino acids 60 - 110 of BHLHA15.
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Isotyp
- IgG
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Applikationshinweise
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BHLHA15 antibody can be used for detection of BHLHA15 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- BHLHA15 antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- BHLHA15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))
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Andere Bezeichnung
- BHLHA15
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Hintergrund
- BHLHA15 (basic helix-loop-helix protein 15), also known as MIST1 (muscle intestine and stomach expression 1) belongs to the bHLH family of transcription factors and plays a role in regulating the transcriptional activity of MYOD1 in muscle cell development as well as serving as a key regulator of acinar cell function (1,2). BHLHA15 contains a basic helix-loop-helix (bHLH) domain and is capable of binding to E-box motifs as a homodimer or a heterodimer with E-proteins. It may also negatively regulate bHLH-mediated transcription through a N-terminal repressor domain (3). It is expressed in mammary epithelial cells and is essential for the regulation of mammary gland development (4).
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Molekulargewicht
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Predicted: 21 kDa
Observed: 24 kDa -
Gen-ID
- 168620
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NCBI Accession
- NP_803238
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UniProt
- Q7RTS1
Target
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