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Aspartate beta Hydroxylase Antikörper (Middle Region)

ASPH Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN950540
  • Target Alle Aspartate beta Hydroxylase (ASPH) Antikörper anzeigen
    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-331, Middle Region
    Reaktivität
    • 64
    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 58
    • 6
    Kaninchen
    Klonalität
    • 61
    • 3
    Polyklonal
    Konjugat
    • 33
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Aspartate beta Hydroxylase Antikörper ist unkonjugiert
    Applikation
    • 46
    • 26
    • 25
    • 13
    • 13
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to ASPH.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 301-331 amino acids from the Central region of human ASPH
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ASPH Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) sodium azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))
    Andere Bezeichnung
    ASPH (ASPH Produkte)
    Synonyme
    AAH antikoerper, BAH antikoerper, CASQ2BP1 antikoerper, HAAH antikoerper, JCTN antikoerper, junctin antikoerper, 2310005F16Rik antikoerper, 3110001L23Rik antikoerper, AI848629 antikoerper, AW261690 antikoerper, AW561901 antikoerper, C79816 antikoerper, cI-37 antikoerper, aah antikoerper, bah antikoerper, jctn antikoerper, MGC107896 antikoerper, cb971 antikoerper, fb69e10 antikoerper, fc06d04 antikoerper, fc95a08 antikoerper, wu:fb69e10 antikoerper, wu:fc06d04 antikoerper, wu:fc95a08 antikoerper, aspartate beta-hydroxylase antikoerper, aspartate-beta-hydroxylase antikoerper, aspartate beta-hydroxylase L homeolog antikoerper, ASPH antikoerper, Asph antikoerper, asph antikoerper, asph.L antikoerper
    Hintergrund
    This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.Synonyms: ASP beta-hydroxylase, Aspartate beta-hydroxylase, Aspartyl/asparaginyl beta-hydroxylase, HAAH, JCTN, Peptide-aspartate beta-dioxygenase, junctin
    Gen-ID
    444
    NCBI Accession
    NP_001158222
    Pathways
    Positive Regulation of Endopeptidase Activity
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