AMH Antikörper (Middle Region)

Produktnummer ABIN950438

Der Kaninchen Polyklonal Anti-AMH-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, AMH in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für AMH Antikörper (Middle Region) (ABIN950438)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AMH Antikörper

Bindungsspezifität: AA 430-460, Middle Region

Spezifität: This antibody reacts to Anti-Muellerian Hormone.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 430~460 amino acids from the Central region of human AMH

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-AMH Antikörper (ABIN950438)

Segal, Kent, Wesche, Ng, Serra, Oulès, Kar, Emerton, Blackford, Darmanis, Miquel, Luong, Yamamoto, Bonham, Jassem, Heaton, Vigilante, King, Sancho, Teichmann, Quake, Nakauchi, Rashid: "Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors." in: Nature communications, Vol. 10, Issue 1, pp. 3350, (2019) (PubMed).

Details zu AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Andere Bezeichnung: Anti-Muellerian Hormone / AMH

Hintergrund: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.Synonyms: MIF, MIS, Muellerian-inhibiting factor, Muellerian-inhibiting substance

Gen-ID: 268

NCBI Accession: NP_000470

Pathways: Negative Regulation of Hormone Secretion