AMH Antikörper (AA 424-451)
Kurzübersicht für AMH Antikörper (AA 424-451) (ABIN653897)
Target
Alle AMH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 424-451
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids of human AMH.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:2000. IHC-P: 1:25. FC: 1:25
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "FOXL2 Is an Essential Activator of SF-1-Induced Transcriptional Regulation of Anti-Müllerian Hormone in Human Granulosa Cells." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159112, (2017) (PubMed).
: "Positive cross talk between FOXL2 and antimüllerian hormone regulates ovarian reserve." in: Fertility and sterility, (2014) (PubMed).
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- AMH (Anti-Mullerian Hormone (AMH))
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Andere Bezeichnung
- AMH
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Hintergrund
- Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
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Molekulargewicht
- 59195
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Gen-ID
- 268
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NCBI Accession
- NP_000470
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UniProt
- P03971
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Pathways
- Negative Regulation of Hormone Secretion
Target
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