Ensa Antikörper (Middle Region)

Produktnummer ABIN950376

Dieses Anti-Ensa-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ensa in WB, FACS und EIA. Geeignet für Human und Maus.

Kurzübersicht für Ensa Antikörper (Middle Region) (ABIN950376)

Target: Ensa (ENSA) (Endosulfine alpha (ENSA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ensa Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-Ensa Antikörper

Bindungsspezifität: AA 46-74, Middle Region

Spezifität: This antibody recognizes Human and Mouse Alpha-endosulfine (ENSA) (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 46-74 amino acids from the Central region of Human ENSA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Ensa

Target: Ensa (ENSA) (Endosulfine alpha (ENSA))

Andere Bezeichnung: alpha-Endosulfine (ENSA)

Hintergrund: ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.Synonyms: ARPP-19e

Molekulargewicht: 13389 Da

Gen-ID: 2029

NCBI Accession: NP_004427