Actin-Like 7A Antikörper (N-Term)
Kurzübersicht für Actin-Like 7A Antikörper (N-Term) (ABIN950263)
Target
Alle Actin-Like 7A (ACTL7A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 48-75, N-Term
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Spezifität
- This antibody reacts to ACTL7A.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human ACTL7A
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Actin-Like 7A (ACTL7A)
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Andere Bezeichnung
- ACTL7A
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Hintergrund
- ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.Synonyms: Actin-like protein 7A, Actin-like-7-alpha
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Gen-ID
- 10881
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NCBI Accession
- NP_006678
Target
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