Actin-Like 7A Antikörper (N-Term)

Produktnummer ABIN654426

Der Kaninchen Polyklonal anti-Actin-Like 7A Antikörper (Klon RB22393) (ABIN654426) detektiert spezifisch Actin-Like 7A in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Actin-Like 7A Antikörper (N-Term) (ABIN654426)

Target: Actin-Like 7A (ACTL7A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Actin-Like 7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB22393

Produktdetails anti-Actin-Like 7A Antikörper

Bindungsspezifität: AA 41-67, N-Term

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Actin-Like 7A

Target: Actin-Like 7A (ACTL7A)

Andere Bezeichnung: ACTL7A

Hintergrund: ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.

Molekulargewicht: 48644

Gen-ID: 10881

NCBI Accession: NP_006678

UniProt: Q9Y615