HSD17B3 Antikörper (Middle Region)

Produktnummer ABIN950183

Der Kaninchen Polyklonal Anti-HSD17B3-Antikörper wurde für WB, FACS, IHC (p) und EIA validiert. Er ist geeignet, HSD17B3 in Proben von Human zu detektieren.

Kurzübersicht für HSD17B3 Antikörper (Middle Region) (ABIN950183)

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-HSD17B3 Antikörper

Bindungsspezifität: AA 96-126, Middle Region

Spezifität: This antibody recognizes Human 17-beta-HSD3 / HSD17B3 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 96~126 amino acids from the Central region of human 17-beta-HSD3 / HSD17B3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Andere Bezeichnung: 17-beta-HSD3 / HSD17B3

Hintergrund: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.Synonyms: 17-beta-hydroxysteroid dehydrogenase type 3, EDH17B3, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3

Molekulargewicht: 34516 Da

Gen-ID: 3293

NCBI Accession: NP_000188

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis