HSD17B3 Antikörper (N-Term)

Produktnummer ABIN2785439

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-HSD17B3 Antikörper wird verwendet zum Nachweis von HSD17B3 in Proben von Human, Ratte und Pferd. Er wurde validiert für WB.

Kurzübersicht für HSD17B3 Antikörper (N-Term) (ABIN2785439)

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reaktivität: Human, Ratte, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HSD17B3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HSD17B3 Antibody - N-terminal region

Sequenz: AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV

Homologie: Horse: 79%, Human: 100%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD17B3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53554-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HSD17B3 Antikörper (ABIN2785439)

Bertin, Dury, Ouellet, Pelletier, Labrie: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).

Details zu HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Andere Bezeichnung: HSD17B3

Hintergrund:

Background Information: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

Gene Name: Hydroxysteroid (17-beta) dehydrogenase 3

Alternative Symbols: EDH17B3, SDR12C2

Protein Name: Testosterone 17-beta-dehydrogenase 3

Molekulargewicht: 34kDa

Gen-ID: 3293

NCBI Accession: NP_000188

UniProt: P37058

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis