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B-Cell Linker Antikörper (AA 171-356)

BLNK Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN94495
  • Target Alle B-Cell Linker (BLNK) Antikörper anzeigen
    B-Cell Linker (BLNK)
    Bindungsspezifität
    • 28
    • 22
    • 17
    • 15
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-356
    Reaktivität
    • 110
    • 74
    • 38
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 112
    • 15
    • 1
    Kaninchen
    Klonalität
    • 107
    • 21
    Polyklonal
    Konjugat
    • 53
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    Dieser B-Cell Linker Antikörper ist unkonjugiert
    Applikation
    • 110
    • 52
    • 36
    • 26
    • 26
    • 19
    • 18
    • 8
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    The polyclonal antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).
    Kreuzreaktivität (Details)
    Mouse
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    A fusion protein representing amino acids 171-356 of human BLNK.
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  • Applikationshinweise
    Western blotting: Reducing conditions.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    B-Cell Linker (BLNK)
    Andere Bezeichnung
    SLP65 / BLNK (BLNK Produkte)
    Synonyme
    BLNK antikoerper, blnk antikoerper, MGC147045 antikoerper, BASH antikoerper, Bca antikoerper, Ly-57 antikoerper, Ly57 antikoerper, Lyw-57 antikoerper, SLP-65 antikoerper, AGM4 antikoerper, BLNK-S antikoerper, LY57 antikoerper, SLP65 antikoerper, bca antikoerper, B-cell linker antikoerper, B cell linker antikoerper, BLNK antikoerper, blnk antikoerper, Blnk antikoerper
    Hintergrund
    B cell linkerprovided,SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa, B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins, thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.,SLP65, BASH, Ly57
    Gen-ID
    29760
    UniProt
    Q8WV28
    Pathways
    BCR Signaling
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