B-Cell Linker Antikörper (AA 171-356)
Kurzübersicht für B-Cell Linker Antikörper (AA 171-356) (ABIN94495)
Target
Alle B-Cell Linker (BLNK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 171-356
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Verwendungszweck
- Anti-Ms Blnk Purified
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Spezifität
- The polyclonal antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).
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Kreuzreaktivität (Details)
- Mouse
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- A fusion protein representing amino acids 171-356 of human BLNK.
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anti-B-Cell Linker (BLNK) antibody
BLNK Reaktivität: Human, Maus WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 5G9 unconjugated
anti-B-Cell Linker (BLNK) (AA 65-314) antibodyBLNK Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (C-Term) antibodyVerified BLNK Reaktivität: Human WB, ELISA, FACS, IF Wirt: Ziege Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 301-400) antibodyBLNK Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 1D7 unconjugated
anti-B-Cell Linker (BLNK) (AA 41-337) antibodyBLNK Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK Reaktivität: Human WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 150-178) antibodyBLNK Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18883 unconjugated
anti-B-Cell Linker (BLNK) (N-Term) antibodyBLNK Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr84) antibodyBLNK Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Western blotting: Reducing conditions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- B-Cell Linker (BLNK)
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Andere Bezeichnung
- Blnk
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Hintergrund
- B cell linkerprovided,SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa, B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins, thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.,SLP65, BASH, Ly57
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Gen-ID
- 29760
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UniProt
- Q8WV28
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Pathways
- BCR Signaling
Target
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