MICA Antikörper
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- Target Alle MICA Antikörper anzeigen
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MICA Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The antibody MEM-81 reacts with an extracellular epitope on human classical MHC Class I molecules in native cell-surface forms. MHC Class I molecules (MHC Class Ia) are expressed on the surface of human nucleated cell types.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Leukocytes of a patient suffering with LGL type leukemia.
- Klon
- MEM-81
- Isotyp
- IgG1
- Top Product
- Discover our top product MICA Primärantikörper
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- Andere Bezeichnung
- HLA-Class I (MICA Produkte)
- Synonyme
- MIC-A antikoerper, PERB11.1 antikoerper, MHC class I polypeptide-related sequence A antikoerper, MICA antikoerper
- Hintergrund
- HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
- Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis
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