CD59 Antikörper
(2 Referenzen)-
- Target Alle CD59 Antikörper anzeigen
- CD59
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Reaktivität
- Human, Schwein
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD59 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Functional Studies (Func)
- Spezifität
- The antibody MEM-129 reacts with CD59 (Protectin), a 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored extracellular glycoprotein expressed on all hematopoietic cells, it is widely present on cells in all tissus.
- Kreuzreaktivität (Details)
- Human, Porcine
- Aufreinigung
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human peripheral blood lymphocytes
- Klon
- MEM-129
- Isotyp
- IgM
- Top Product
- Discover our top product CD59 Primärantikörper
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anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reaktivität: Human FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 8D2B8 unconjugated
anti-CD59 (CD59) (AA 74-110) antibodyCD59 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB56691 unconjugated
anti-CD59 (CD59) antibodyCD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 unconjugated
anti-CD59 (CD59) antibodyCD59 Reaktivität: Human, Maus WB, FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43-5 unconjugated
anti-CD59 (CD59) (AA 31-111) antibodyCD59 Reaktivität: Human WB, FACS, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated
anti-CD59 (CD59) (AA 23-105) antibodyCD59 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD59 (CD59) (AA 1-128) antibodyCD59 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3G6 unconjugated
anti-CD59 (CD59) (AA 26-102) antibodyCD59 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD59 (CD59) antibody (Biotin)CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 Biotin
anti-CD59 (CD59) antibody (FITC)CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC
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- Applikationshinweise
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Functional application: The antibody MEM-129 activates T cells.
Flow cytometry: Recommended dilution: 1-4 μg/mL. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- HEPES buffered saline (HBS), pH 7.0
- Konservierungsmittel
- Azide free
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19242-7, (1997) (PubMed).
: "CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells." in: Blood, Vol. 85, Issue 9, pp. 2402-13, (1995) (PubMed).
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: "Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19242-7, (1997) (PubMed).
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- Target
- CD59
- Andere Bezeichnung
- CD59 (CD59 Produkte)
- Hintergrund
- CD59 Molecule,CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.,MACIF, MAC-IP, protectin, MIRL, HRF-20, HRF20, 1F5, MIN
- Gen-ID
- 966
- UniProt
- P13987
- Pathways
- Komplementsystem
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