CD55 Antikörper

Produktnummer ABIN94183

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD55 in WB, FACS, IP und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Non-Human Primate und wurde in 1 Publikation erwähnt.

Kurzübersicht für CD55 Antikörper (ABIN94183)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: MEM-118

Produktdetails anti-CD55 Antikörper

Verwendungszweck: Anti-Hu CD55 Purified

Spezifität: The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain extracellular glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.

Kreuzreaktivität (Details): Human, Non-Human Primates

Aufreinigung: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: HPB-ALL human T cell line

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 10 μg/mL.
Immunohistochemistry (paraffin sections): Heat-mediated antigen retrieval, recommended dilution: 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-CD55 Antikörper (ABIN94183)

Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55

Hintergrund: CD55 Molecule (Cromer blood group),CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.,DAF, CROM, CHAPLE

Gen-ID: 1604

UniProt: P08174

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity