CD33 Antikörper (Biotin)
(1 reference)Kurzübersicht für CD33 Antikörper (Biotin) (ABIN94073)
Target
Alle CD33 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD33 Biotin
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Kreuzreaktivität (Details)
- Human, Non-Human Primates
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Produktmerkmale
- The antibody HIM3-4 reacts with an extracellular epitope of CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
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Aufreinigung
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
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Immunogen
- NFMY-9s human cell line
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Isotyp
- IgG1
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anti-CD33 (CD33) (AA 101-200) antibody
CD33 Reaktivität: Human, Maus FACS, WB, ELISA, IHC (fro), ICC, IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 Reaktivität: Human FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, MS Wirt: Maus Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, MS Wirt: Maus Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibody (FITC)CD33 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal WM53 FITC
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-12 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." in: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).
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: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." in: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).
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- CD33
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Andere Bezeichnung
- CD33
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Hintergrund
- CD33 Molecule,CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.,SIGLEC3, p67
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Gen-ID
- 945
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UniProt
- P20138
Target
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