CD33 Antikörper (AA 15-237)
(2 Referenzen)-
- Target Alle CD33 Antikörper anzeigen
- CD33
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Bindungsspezifität
- AA 15-237
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD33 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. coli.
- Klon
- 2C6B7
- Isotyp
- IgG1
- Top Product
- Discover our top product CD33 Primärantikörper
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anti-CD33 (CD33) (AA 101-200) antibody
CD33 Reaktivität: Human, Maus FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 Reaktivität: Human FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD33 (CD33) (AA 18-269) antibodyCD33 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM77 unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, CyTOF Wirt: Maus Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibodyCD33 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, CyTOF Wirt: Maus Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibody (Biotin)CD33 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal HIM3-4 Biotin
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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: "The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).
: "A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting." in: mAbs, Vol. 3, Issue 1, pp. 21-30, (2011) (PubMed).
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: "The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).
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- Target
- CD33
- Andere Bezeichnung
- CD33 (CD33 Produkte)
- Synonyme
- SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper
- Hintergrund
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Description: The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)
Aliases: p67, SIGLEC3, SIGLEC-3
- Molekulargewicht
- 39.8 kDa
- Gen-ID
- 945
- HGNC
- 945
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