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beta-2 Microglobulin Antikörper (FITC)

This anti-beta-2 Microglobulin antibody (ABIN93905) is a Mouse Monoclonal antibody detecting beta-2 Microglobulin in FACS. Suitable for Human.
Produktnummer ABIN93905

Kurzübersicht für beta-2 Microglobulin Antikörper (FITC) (ABIN93905)

Target

Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität

  • 244
  • 69
  • 38
  • 27
  • 9
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 160
  • 138
  • 9
  • 6
  • 2
  • 1
Maus

Klonalität

  • 165
  • 150
  • 1
Monoklonal

Konjugat

  • 166
  • 35
  • 28
  • 14
  • 14
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser beta-2 Microglobulin Antikörper ist konjugiert mit FITC

Applikation

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  • 17
  • 14
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  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

B2M-01
  • Verwendungszweck

    Anti-Hu beta2-Microglobulin FITC

    Spezifität

    The mouse monoclonal antibody B2M-01 reacts with beta2-microglobulin (beta2M, extracellular antigen), associated with cell-surface MHC Class I molecules and other membrane antigens, as well as it reacts with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.

    Keine Kreuzreaktivität

    Huhn, Rind (Kuh), Hund, Maus, Kaninchen

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    Purified human beta2-microglobulin

    Isotyp

    IgG2a
  • Applikationshinweise

    Flow cytometry: Recommended dilution: 1 μg/mL, positive control: peripheral blood lymphocytes, negative control: DAUDI human Burkitt lymphoma cell line, erythrocytes.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Poláková, Železníková, Russ: "HLA-G5 in the blood of leukemia patients and healthy individuals." in: Leukemia research, Vol. 37, Issue 2, pp. 139-45, (2013) (PubMed).

    Khurana, Traum, Aivado, Wells, Guerrero, Grall, Libermann, Schachter: "Urine proteomic profiling of pediatric nephrotic syndrome." in: Pediatric nephrology (Berlin, Germany), Vol. 21, Issue 9, pp. 1257-65, (2006) (PubMed).

    Lafon, Prehaud, Megret, Lafage, Mouillot, Roa, Moreau, Rouas-Freiss, Carosella: "Modulation of HLA-G expression in human neural cells after neurotropic viral infections." in: Journal of virology, Vol. 79, Issue 24, pp. 15226-37, (2005) (PubMed).

    Hilgert, Horejsí, Kristofová: "The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin." in: Folia biologica, Vol. 30, Issue 6, pp. 369-76, (1985) (PubMed).

  • Target

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    Andere Bezeichnung

    beta2-Microglobulin

    Hintergrund

    Beta-2-microglobulin,Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.,B2M

    Gen-ID

    567

    UniProt

    P61769

    Pathways

    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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