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beta-2 Microglobulin Antikörper (Biotin)

This anti-beta-2 Microglobulin antibody (ABIN93901) is a Mouse Monoclonal antibody detecting beta-2 Microglobulin in WB, FACS, ELISA, IHC (p). Suitable for Human, Pig.
Produktnummer ABIN93901

Kurzübersicht für beta-2 Microglobulin Antikörper (Biotin) (ABIN93901)

Target

Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität

  • 244
  • 69
  • 38
  • 27
  • 9
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Schwein

Wirt

  • 160
  • 138
  • 9
  • 6
  • 2
  • 1
Maus

Klonalität

  • 165
  • 150
  • 1
Monoklonal

Konjugat

  • 166
  • 34
  • 29
  • 14
  • 14
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser beta-2 Microglobulin Antikörper ist konjugiert mit Biotin

Applikation

  • 173
  • 120
  • 108
  • 80
  • 71
  • 70
  • 67
  • 38
  • 26
  • 18
  • 17
  • 14
  • 13
  • 10
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

B2M-02
  • Verwendungszweck

    Anti-Hu beta2-Microglobulin Biotin

    Spezifität

    The mouse monoclonal antibody B2M-02 reacts with beta2-microglobulin (beta2M), an extracellular antigen associated with cell-surface MHC Class I molecules and other membrane antigens, as well as it reacts with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.

    Kreuzreaktivität (Details)

    Human, Porcine

    Aufreinigung

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    Immunogen

    Purified isolated human beta2-microglobulin.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: Recommended dilution: 1-2 μg/mL, positive control: PBL cell line, negative control: DAUDI human lymphoma cell line, erythrocytes.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: "A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells." in: Blood, Vol. 98, Issue 5, pp. 1561-6, (2001) (PubMed).

    Hilgert, Horejsí, Kristofová: "The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin." in: Folia biologica, Vol. 30, Issue 6, pp. 369-76, (1985) (PubMed).

  • Target

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    Andere Bezeichnung

    beta2-Microglobulin

    Hintergrund

    Beta-2-microglobulin,Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.,B2M

    Gen-ID

    567

    UniProt

    P61769

    Pathways

    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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