Resistin Antikörper

Produktnummer ABIN934075

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Resistin in WB, ELISA und Inhibition. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Resistin Antikörper (ABIN934075)

Target: Resistin (RETN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Resistin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Klon: M912287

Produktdetails anti-Resistin Antikörper

Immunogen: Resistin antibody was raised in mouse using highly pure recombinant human resistin as the immunogen.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu Resistin

Target: Resistin (RETN)

Andere Bezeichnung: Resistin

Hintergrund: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Synonyms: Monoclonal Resistin antibody, Anti-Resistin antibody, FIZZ3 antibody, Adipose tissue-specific secretory factor antibody, ADSF antibody.

Molekulargewicht: 20.2 kDa (predicted detection band MW)

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration