Resistin Antikörper
Kurzübersicht für Resistin Antikörper (ABIN1169370)
Target
Alle Resistin (RETN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- anti-Resistin (human), pAb
-
Spezifität
- Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10 kDa by Western blot.
-
Kreuzreaktivität (Details)
- Weakly cross-reacts with mouse resistin.
-
Produktmerkmale
- Polyclonal Antibody. Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
-
Sterilität
- 0.2 μm filtered
-
Immunogen
- Recombinant human resistin.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
-
Konservierungsmittel
- Without preservative
-
Handhabung
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
-
Haltbarkeit
- 6 months
-
-
-
: "Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans." in: Diabetologia, Vol. 47, Issue 3, pp. 559-65, (2004) (PubMed).
-
-
- Resistin (RETN)
-
Andere Bezeichnung
- Resistin
-
Hintergrund
-
Alternate Names/Synonyms: FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor
Product Description: The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
-
UniProt
- Q9HD89
-
Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
-