Optimal conditions should be determined byt he investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as a liquid in PBS.
Konservierungsmittel
Without preservative
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C.
Target
CD3 epsilon (CD3E)
Andere Bezeichnung
CD3e
Hintergrund
CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Synonyms: Monoclonal CD3e antibody, Anti-CD3e antibody.