ERCC6 Antikörper

Produktnummer ABIN932472

Der Maus Monoklonal anti-ERCC6 Antikörper (Klon 553C5a) (ABIN932472) detektiert spezifisch ERCC6 in DB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ERCC6 Antikörper (ABIN932472)

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERCC6 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: 553C5a

Produktdetails anti-ERCC6 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: ERCC6 antibody was raised in mouse using recombinant Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (Ercc6)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: ERCC6 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu ERCC6

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Andere Bezeichnung: ERCC6

Hintergrund: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity, there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B. Synonyms: Monoclonal ERCC6 antibody, Anti-ERCC6 antibody, Excision repair cross complementing rodent repair deficiency, complementation group 6 antibody, CSB antibody, CKN2 antibody, COFS antibody, ARMD5 antibody, COFS1 antibody, RAD26 antibody.

Pathways: DNA Reparatur, Chromatin Binding