RORC Antikörper

Produktnummer ABIN932197

Produktdetails anti-RORC Antikörper

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: RORC antibody was raised in mouse using recombinant Human Rar-Related Orphan Receptor C

Klon: 162C2a

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: RORC antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: RORC (RORC Produkte)

Synonyme: NR1F3 antikoerper, RORG antikoerper, RZR-GAMMA antikoerper, RZRG antikoerper, TOR antikoerper, Nr1f3 antikoerper, RORgamma antikoerper, Thor antikoerper, RAR related orphan receptor C antikoerper, RAR-related orphan receptor C antikoerper, RAR-related orphan receptor gamma antikoerper, RORC antikoerper, Rorc antikoerper

Hintergrund: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. Synonyms: Monoclonal RORC antibody, Anti-RORC antibody, RAR-related orphan receptor C antibody, TOR antibody, RORG antibody, RZRG antibody, NR1F3 antibody, MGC129539 antibody.

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway