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RORC Antikörper (Middle Region)

RORC Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777822
  • Target Alle RORC Antikörper anzeigen
    RORC (RAR-Related Orphan Receptor C (RORC))
    Bindungsspezifität
    • 16
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 96
    • 54
    • 22
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Schwein
    Wirt
    • 79
    • 17
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 82
    • 19
    Polyklonal
    Konjugat
    • 53
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser RORC Antikörper ist unkonjugiert
    Applikation
    • 80
    • 37
    • 24
    • 24
    • 15
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    CHLEYSPERG KAEGRESFYS TGSQLTPDRC GLRFEEHRHP GLGELGQGPD
    Homologie
    Cow: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RORC
    Top Product
    Discover our top product RORC Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 497 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Huang, Huang, Lee, Ng, Chang: "Postirradiation sinus mucosa disease in nasopharyngeal carcinoma patients." in: The Laryngoscope, Vol. 117, Issue 4, pp. 737-42, (2007) (PubMed).

  • Target
    RORC (RAR-Related Orphan Receptor C (RORC))
    Andere Bezeichnung
    RORC (RORC Produkte)
    Synonyme
    NR1F3 antikoerper, RORG antikoerper, RZR-GAMMA antikoerper, RZRG antikoerper, TOR antikoerper, Nr1f3 antikoerper, RORgamma antikoerper, Thor antikoerper, RAR related orphan receptor C antikoerper, RAR-related orphan receptor C antikoerper, RAR-related orphan receptor gamma antikoerper, RORC antikoerper, Rorc antikoerper
    Hintergrund
    RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: MGC129539, NR1F3, RORG, RZRG, TOR, RZR-GAMMA
    Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,
    Protein Size: 497
    Molekulargewicht
    56 kDa
    Gen-ID
    6097
    NCBI Accession
    NM_001001523, NP_001001523
    UniProt
    B3KUU9
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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