Chitotriosidase 1 Antikörper (AA 22-137)

Produktnummer ABIN931480

Produktdetails anti-Chitotriosidase 1 Antikörper

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Bindungsspezifität: AA 22-137

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Chitotriosidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: CHIT1 antibody was raised in Mouse using a purified recombinant fragment of CHIT1(aa22-137) expressed in E. coli as the immunogen.

Klon: 1D9G2-1D9G4-2B4G3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Details zu Chitotriosidase 1

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Andere Bezeichnung: CHIT1 (CHIT1 Produkte)

Synonyme: CHI3 antikoerper, CHIT antikoerper, CHITD antikoerper, CHIT1 antikoerper, chio antikoerper, 2300002L19Rik antikoerper, chitinase 1 antikoerper, chitinase 1 (chitotriosidase) antikoerper, CHIT1 antikoerper, chit1 antikoerper, Chit1 antikoerper

Hintergrund: CHIT1 is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Synonyms: Monoclonal CHIT1 antibody, Anti-CHIT1 antibody, Chitinase 1 antibody, Chitotriosidase antibody, CHIT antibody.