Chitotriosidase 1 Antikörper (AA 22-137)

Produktnummer ABIN969053

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-Chitotriosidase 1 Antikörper wird verwendet zum Nachweis von Chitotriosidase 1 in Proben von Human. Er wurde validiert für ELISA.

Kurzübersicht für Chitotriosidase 1 Antikörper (AA 22-137) (ABIN969053)

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Chitotriosidase 1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1D9G2

Produktdetails anti-Chitotriosidase 1 Antikörper

Bindungsspezifität: AA 22-137

Verwendungszweck: CHIT1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Chitotriosidase 1 Antikörper (ABIN969053)

Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: "Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ..." in: Clinical biochemistry, Vol. 40, Issue 5-6, pp. 365-9, (2007) (PubMed).

Bargagli, Margollicci, Perrone, Luddi, Perari, Bianchi, Refini, Grosso, Volterrani, Rottoli: "Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis." in: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders, Vol. 24, Issue 1, pp. 59-64, (2007) (PubMed).

Details zu Chitotriosidase 1

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Andere Bezeichnung: CHIT1

Hintergrund: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Molekulargewicht: 52 kDa

Gen-ID: 1118

UniProt: Q13231