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SYK Antikörper (AA 296-484)

SYK Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 8C1A3 unconjugated
Produktnummer ABIN931471
  • Target Alle SYK Antikörper anzeigen
    SYK (Spleen tyrosine Kinase (SYK))
    Bindungsspezifität
    • 29
    • 22
    • 19
    • 16
    • 10
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-484
    Reaktivität
    • 173
    • 87
    • 53
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 156
    • 22
    • 3
    Maus
    Klonalität
    • 159
    • 21
    Monoklonal
    Konjugat
    • 104
    • 12
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SYK Antikörper ist unkonjugiert
    Applikation
    • 147
    • 83
    • 46
    • 25
    • 22
    • 18
    • 14
    • 14
    • 12
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Immunogen
    SYK antibody was raised in Mouse using a purified recombinant fragment of SYK(aa296-484) expressed in E. coli as the immunogen.
    Klon
    8C1A3
    Isotyp
    IgG1
    Top Product
    Discover our top product SYK Primärantikörper
  • Applikationshinweise
    ELISA: 1:10,000, WB: 1:500-1:2000
    Optimal conditions should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • Target
    SYK (Spleen tyrosine Kinase (SYK))
    Andere Bezeichnung
    SYK (SYK Produkte)
    Synonyme
    p72-Syk antikoerper, Sykb antikoerper, p72syk antikoerper, spleen associated tyrosine kinase antikoerper, spleen tyrosine kinase antikoerper, syk antikoerper, SYK antikoerper, Syk antikoerper
    Hintergrund
    SYK is a non-receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Synonyms: Monoclonal SYK antibody, Anti-SYK antibody, Spleen tyrosine kinase antibody.
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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