Aurora Kinase B Antikörper

Produktnummer ABIN931443

Der Maus Monoklonal anti-Aurora Kinase B Antikörper (Klon 13E8D3) (ABIN931443) detektiert spezifisch Aurora Kinase B in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Aurora Kinase B Antikörper (ABIN931443)

Target: Aurora Kinase B (AURKB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aurora Kinase B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 13E8D3

Produktdetails anti-Aurora Kinase B Antikörper

Immunogen: AURKB antibody was raised in Mouse using a purified recombinant fragment of AURKB expressed in E. coli as the immunogen.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Details zu Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Andere Bezeichnung: AURKB

Hintergrund: The aurora family (A, B and C) are serine threonine kinases and key regulators of chromosome segregation during mitosis. Aurora kinase B is a chromosomal passenger protein that regulates chromosome segregation and cytokinesis. Aurora kinase B is associated with the level of genetic instability within tumours and patient survival. It is strongly expressed in exponentially proliferating bronchial epithelial cells in culture and that this expression is markedly reduced in confluent cells. It is also shown that almost all tumours show higher levels of Aurora kinase B expression than their matched normal lung tissues, which could therefore simply be a consequence of a higher proliferative index, or be typical of the progenitor cell and atypical of the bulk of normal lung cells. Synonyms: Monoclonal AURKB antibody, Anti-AURKB antibody, Serine/threonine-protein kinase 12 antibody, Aurora-B antibody, AIK2 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, aurkb-sv1 antibody, aurkb-sv2 antibody, IPL1 antibody, STK12 antibody, aurkb antibody, AIM1 antibody, AURKB antibody, Aurora 1 antibody, STK1 antibody, STK5 antibody, Aurora and Ipl1 like midbody associated protein 1 antibody, Aurora kinase B antibody, Aurora related kinase 2 antibody, Aurora/IPL1 related kinase 2 antibody, Serine/theronine kinase 12 antibody, Serine/threonine protein kinase 12 antibody.

Pathways: T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades