CD3 epsilon Antikörper

Produktnummer ABIN931331

Der Maus Monoklonal anti-CD3 epsilon Antikörper wird verwendet zum Nachweis von CD3 epsilon in Proben von Human. Er wurde validiert für FACS, WB und ELISA.

Kurzübersicht für CD3 epsilon Antikörper (ABIN931331)

Target: CD3 epsilon (CD3E)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 epsilon Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Klon: 4E2

Produktdetails anti-CD3 epsilon Antikörper

Immunogen: CD3 E antibody was raised in Mouse using a purified recombinant fragment of CD3 expressed in E. coli as the immunogen.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, FC: 1:200-1:400, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Details zu CD3 epsilon

Target: CD3 epsilon (CD3E)

Andere Bezeichnung: CD3E

Hintergrund: CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Synonyms: Monoclonal CD3E antibody, Anti-CD3E antibody, CD3 epsilon antibody.

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway