CBFB Antikörper

Produktnummer ABIN931127

Der Maus Monoklonal Anti-CBFB-Antikörper wurde für WB, ICC und DB validiert. Er ist geeignet, CBFB in Proben von Human zu detektieren.

Kurzübersicht für CBFB Antikörper (ABIN931127)

Target: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CBFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Klon: 344C3a

Produktdetails anti-CBFB Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: CBFB antibody was raised in mouse using recombinant Human Core-Binding Factor, Beta Subunit

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: CBFB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu CBFB

Target: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Andere Bezeichnung: CBFB

Hintergrund: The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Synonyms: Monoclonal CBFB antibody, Anti-CBFB antibody, Core-binding factor subunit beta antibody, PEBP2B antibody.

Pathways: Regulation of Lipid Metabolism by PPARalpha