PPP1R13L
Reaktivität: Human
WB, ELISA
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
WB: 0.2-2 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
PPP1 R11 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
Target
PPP1R13L
(Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))
Andere Bezeichnung
PPP1R13L
Hintergrund
PPP1R13L is a regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. It also blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis{EC1,EC2,EC3,EC4}. Synonyms: Monoclonal PPP1R13L antibody, Anti-PPP1R13L antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 13 like antibody, RAI antibody, IASPP antibody, NKIP1 antibody, iASPP gene antibody.