GTF2H2 Antikörper

Produktnummer ABIN930961

Dieser Maus Monoklonal Antikörper detektiert spezifisch GTF2H2 in DB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GTF2H2 Antikörper (ABIN930961)

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GTF2H2 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: GTF2F6A10

Produktdetails anti-GTF2H2 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: GTF2 H2 antibody was raised in mouse using recombinant Human General Transcription Factor Iih, Polypeptide 2, 42 da

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: GTF2 H2 antibody in PBS (3.0 mM KCl,1.5 mM KH2 O4, 140 mM NaCl, 8.0 mM Na2 P04 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu GTF2H2

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Andere Bezeichnung: GTF2H2

Hintergrund: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Synonyms: Monoclonal GTF2H2 antibody, Anti-GTF2H2 antibody, General transcription factor IIH subunit 2 antibody, BTF2 antibody, TFIIH antibody, BTF2P44 antibody, T-BTF2P44 antibody.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling